Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 10/20 | 0.47 |
| ▸ | IDO1 | P14902 | 8/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.47 |
| ▸ | APAF1 | O14727 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26857588 | 0.89 | TDO2 (0.43) | TDO2IDO1IDO2APAF1AGTR1 | |
| SCHEMBL30639071 | 0.89 | TDO2 (0.43) | TDO2IDO1IDO2APAF1AGTR1 | |
| SCHEMBL26614260 | 0.76 | TDO2 (0.52) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL30639102 | 0.73 | TDO2 (0.42) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL26857739 | 0.71 | IDO1 (0.69) | TDO2IDO1IDO2APAF1MEN1 | |
| Hydrochloric Acid SCHEMBL26614206 | 0.71 | TDO2 (0.68) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL26614121 | 0.69 | IDO1 (0.70) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL9220971 | 0.69 | TDO2 (0.66) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL9222336 | 0.68 | TDO2 (0.63) | TDO2IDO1IDO2APAF1MEN1 | |
| SCHEMBL24513682 | 0.68 | APAF1 (0.67) | TDO2IDO1IDO2APAF1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |