Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 16/20 | 0.52 |
| ▸ | IDO1 | P14902 | 15/20 | 0.52 |
| ▸ | IDO2 | Q6ZQW0 | 10/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL26614295 | 0.99 | TDO2 (0.52) | TDO2IDO1IDO2CCNCCDK8 | |
| Hydrochloric Acid SCHEMBL30639052 | 0.99 | TDO2 (0.52) | TDO2IDO1IDO2CCNCCDK8 | |
| SCHEMBL26614169 | 0.85 | TDO2 (0.58) | TDO2IDO1IDO2CCNCCDK8 | |
| SCHEMBL26614240 | 0.85 | TDO2 (0.54) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL30639059 | 0.79 | APAF1 (0.53) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL26614187 | 0.79 | APAF1 (0.53) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL26614260 | 0.77 | TDO2 (0.52) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL30639061 | 0.77 | TDO2 (0.63) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL30639103 | 0.77 | TDO2 (0.56) | TDO2IDO1IDO2APAF1 | |
| SCHEMBL26614153 | 0.77 | TDO2 (0.63) | TDO2IDO1IDO2APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |