Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 8/20 | 0.51 |
| ▸ | TDO2 | P48775 | 7/20 | 0.47 |
| ▸ | IDO2 | Q6ZQW0 | 7/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614187 | 1.00 | APAF1 (0.53) | APAF1IDO1TDO2IDO2CASP1 | |
| SCHEMBL26614178 | 0.86 | ADORA2A (0.44) | APAF1IDO1TDO2IDO2HRH4 | |
| SCHEMBL30639084 | 0.86 | ADORA2A (0.44) | APAF1IDO1TDO2IDO2HRH4 | |
| SCHEMBL26614124 | 0.84 | IDO1 (0.55) | APAF1IDO1TDO2IDO2CASP1 | |
| SCHEMBL30639089 | 0.84 | IDO1 (0.55) | APAF1IDO1TDO2IDO2CASP1 | |
| SCHEMBL26614168 | 0.82 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639101 | 0.82 | APAF1 (0.67) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL30639072 | 0.81 | APAF1 (0.62) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26614157 | 0.81 | APAF1 (0.62) | APAF1IDO1TDO2IDO2EGFR | |
| SCHEMBL26857592 | 0.79 | TDO2 (0.52) | APAF1IDO1TDO2IDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4514804-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | Viscient Bio, Inc. (US) | 2025-03-05 | — | — | EP | disclosed |
| WO-2023211977-A1 | TRYPTANTHRIN DERIVATIVES AND USES THEREOF | VISCIENT BIO, INC. (US) | 2023-11-02 | — | — | WO | disclosed |