Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26862955 | 0.91 | NPSR1 (0.50) | SIRT1NPSR1MAPTTDP1SIRT2 | |
| SCHEMBL23766786 | 0.88 | SIRT1 (0.50) | SIRT1NPSR1MAPTTDP1SIRT2 | |
| SCHEMBL21802410 | 0.88 | SIRT1 (0.60) | SIRT1SIRT2 | |
| SCHEMBL30409548 | 0.88 | SIRT1 (0.60) | SIRT1SIRT2 | |
| SCHEMBL26862910 | 0.88 | SIRT1 (0.49) | SIRT1NPSR1MAPTTDP1SIRT2 | |
| SCHEMBL26860228 | 0.87 | SIRT1 (0.53) | SIRT1SIRT2 | |
| SCHEMBL26863095 | 0.87 | SIRT1 (0.48) | SIRT1NPSR1MAPTTDP1SIRT2 | |
| SCHEMBL23766644 | 0.87 | SIRT1 (0.48) | SIRT1NPSR1MAPTTDP1SIRT2 | |
| SCHEMBL21891815 | 0.86 | SIRT1 (0.58) | SIRT1SIRT2 | |
| SCHEMBL21891743 | 0.85 | SIRT1 (0.57) | SIRT1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827586-B2 | Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827586-B2 | Method for producing amino acid aminoalkyl ester or inorganic acid salt thereof | SLC6A15, SLC6A19, ALAD | SIRT1 4832/4885NPSR1 2331/4885MAPT 4033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.