SCHEMBL2686211

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3055529	0.84	CHRNB4 (0.52)	MAPTCYP19A1LMNAABCG2PTGS1
	SCHEMBL5960698	0.82	DYRK1A (0.55)	MAPTCYP19A1LMNAPTGS1PTGS2
	SCHEMBL1689880	0.79	ERN1 (0.43)	MAPTCYP19A1LMNAPTGS1PTGS2
	SCHEMBL309863	0.77	LMNA (0.61)	MAPTCYP19A1LMNAPTGS1PTGS2
	SCHEMBL8008016	0.77	PTGS1 (0.59)	MAPTCYP19A1LMNAPTGS1PTGS2
	SCHEMBL2684708	0.77	KMT2A (0.52)	MAPTAHRHTTMEN1KMT2A
	Ethylene SCHEMBL27534902	0.76	PTGS1 (0.59)	MAPTLMNAPTGS1PTGS2HTT
	SCHEMBL1689828	0.75	CYP1A1 (0.49)	MAPTCYP19A1LMNAABCG2PTGS1
	SCHEMBL4610120	0.75	SMN1; SMN2 (0.50)	MAPTLMNAHTTMEN1KMT2A
	SCHEMBL29175169	0.73	KDM4E (0.67)	LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.