Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686605 | 0.87 | APEX1 (0.39) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2687407 | 0.86 | MAPT (0.41) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2685891 | 0.85 | THRB (0.37) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2686719 | 0.84 | APEX1 (0.37) | MAPTALDH1A1ITGA4APEX1PDK2 | |
| SCHEMBL2685794 | 0.83 | SOAT1 (0.41) | APEX1PDK2MEN1KMT2APOLB | |
| SCHEMBL16034381 | 0.83 | THRB (0.48) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2687643 | 0.83 | PDK2 (0.37) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2688645 | 0.83 | SLC25A5 (0.40) | MAPTALDH1A1ITGA4THRBTDP1 | |
| SCHEMBL2688073 | 0.82 | SOAT1 (0.43) | PDK2 | |
| SCHEMBL2687701 | 0.82 | SOAT1 (0.43) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3118226-A1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF Corporation (US) | 2017-01-18 | — | — | EP | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | claimed |
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | claimed |
| EP-2782938-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF Corporation (US) | 2014-10-01 | — | — | EP | claimed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | claimed |
| US-8227370-B2 | High activity catalyst component for olefin polymerization and method of using the same | BASF CORPORATION (US) | 2012-07-24 | — | — | US | claimed |
| CN-102574954-A | Internal donor for olefin polymerization catalysts | BASF CATALYSTS LLC | 2012-07-11 | — | — | CN | claimed |
| US-20120116031-A1 | High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same | BASF CORPORATION (US) | 2012-05-10 | — | — | US | claimed |
| CN-107207657-B | Process for preparing spherical polymerization catalyst components for olefin polymerization | 格雷斯公司 | 2020-03-03 | — | — | CN | disclosed |
| EP-3118226-A1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF Corporation (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| CN-102574954-B | Internal donor for olefin polymerization catalysts | BASF SE | 2014-11-19 | — | — | CN | disclosed |
| CN-102834420-B | Internal and external donor compounds for olefin polymerization catalysts ii | BASF CORP. (US) | 2014-10-22 | — | — | CN | disclosed |
| EP-2782938-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF Corporation (US) | 2014-10-01 | — | — | EP | disclosed |
| CN-104053682-A | High activity catalyst component for olefin polymerization and method of using the same | BASF SE | 2014-09-17 | — | — | CN | disclosed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | disclosed |
| CN-102656194-A | Mixed donor system for high melt flow and high activity | BASF CORP | 2012-09-05 | — | — | CN | disclosed |
| US-8227370-B2 | High activity catalyst component for olefin polymerization and method of using the same | BASF CORPORATION (US) | 2012-07-24 | — | — | US | disclosed |
| CN-102574954-A | Internal donor for olefin polymerization catalysts | BASF CATALYSTS LLC | 2012-07-11 | — | — | CN | disclosed |
| US-20120116031-A1 | High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same | BASF CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |