Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAK | O14976 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26862942 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAMEN1KMT2A | |
| SCHEMBL26862953 | 0.85 | IKBKB (0.38) | ALDH1A1HTTTSHRPTGS1PTGS2 | |
| SCHEMBL26864598 | 0.85 | IKBKB (0.38) | ALDH1A1HTTTSHRPTGS1PTGS2 | |
| SCHEMBL26870392 | 0.84 | ALDH1A1 (0.39) | ALDH1A1HTTLMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL26863377 | 0.83 | GAK (0.39) | HTTPTGS1PTGS2GAK | |
| SCHEMBL26862948 | 0.83 | GAK (0.37) | HTTPTGS1PTGS2GAK | |
| SCHEMBL26862944 | 0.83 | GAK (0.37) | HTTPTGS1PTGS2GAK | |
| SCHEMBL30666120 | 0.82 | BRAF (0.36) | ALDH1A1HTTPTGS1PTGS2GAK | |
| SCHEMBL26865331 | 0.82 | BRAF (0.36) | ALDH1A1HTTPTGS1PTGS2GAK | |
| SCHEMBL26656440 | 0.82 | BRAF (0.36) | ALDH1A1HTTPTGS1PTGS2GAK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023225001-A1 | NAPHTHYRIDINE BASED ENPP1 MODULATORS AND USES THEREOF | Vir Biotechnology, Inc. (US) | 2023-11-23 | — | — | WO | disclosed |