SCHEMBL2686473

SCHEMBL2686473

Cl[SiH](Cl)C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
SRC P12931 1/20 0.42
DPP4 P27487 2/20 0.41
F2 P00734 1/20 0.41
HTR2A P28223 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
CYP2D6 P10635 1/20 0.36
LMNA P02545 2/20 0.35
HRH1 P35367 1/20 0.35
MTOR P42345 1/20 0.35
RAB9A P51151 1/20 0.35
GRM7 Q14831 1/20 0.35
MAPK1 P28482 1/20 0.35
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL297260 0.74 DPP4 (0.46) TSHRSRCDPP4F2TAAR1
SCHEMBL2103006 0.74 TSHR (0.52) TSHRSRCDPP4F2HTR2A
SCHEMBL4074155 0.74 LMNA (0.39) TSHRHTR2ATAAR1LMNAHRH1
SCHEMBL4855633 0.74 TSHR (0.40) TSHRDPP4F2HTR2ACYP2D6
SCHEMBL3894050 0.71 TSHR (0.44) TSHRSRCDPP4F2CYP2D6
SCHEMBL1325499 0.69 DPP4 (0.39) TSHRSRCDPP4F2HTR2A
SCHEMBL10568864 0.65 KMT2A (0.40) TSHRDPP4F2HTR2ATAAR1
SCHEMBL151375 0.65 TSHR (0.65) TSHRSRCDPP4F2HTR2A
SCHEMBL6283476 0.65 TSHR (0.65) TSHRSRCDPP4F2HTR2A
SCHEMBL28353 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111454534-A Preparation method and application of graphene/styrene thermoplastic elastomer 辽宁格莱菲尔健康科技有限公司 2020-07-28 CN claimed
CN-110172157-A A kind of modified organic silicone resin and its preparation method and application 江苏华夏制漆科技有限公司 2019-08-27 CN claimed
EP-3957678-B1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO LTD (JP) 2023-12-13 EP disclosed
US-20220213348-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER TOKYO OHKA KOGYO CO., LTD. (JP) 2022-07-07 US disclosed
EP-3957678-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER Tokyo Ohka Kogyo Co., Ltd. (JP) 2022-02-23 EP disclosed
CN-113480566-A Organic silicon monomer containing diphenylmethane and ultrahigh-refractive-index semiconductor LED packaging material prepared from organic silicon monomer 广州星光有机硅科技有限公司 2021-10-08 CN disclosed
US-11065354-B2 Post-steam sterilization moisture-indicating articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-07-20 US disclosed
WO-2020235325-A1 SILICON-CONTAINING POLYMER, FILM-FORMING COMPOSITION, METHOD FOR SUPPORTING METAL COMPOUND ON SURFACE OF OBJECT TO BE TREATED, ARTICLE HAVING METAL COMPOUND-SUPPORTING COATING FILM, AND METHOD FOR PRODUCING SILICON-CONTAINING POLYMER 東京応化工業株式会社 (JP) 2020-11-26 WO disclosed
CN-111454534-A Preparation method and application of graphene/styrene thermoplastic elastomer 辽宁格莱菲尔健康科技有限公司 2020-07-28 CN disclosed
US-10119918-B2 Adjustable Colorimetric Moisture Indicators 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-11-06 US disclosed
US-20160187309-A1 POST-STEAM STERILIZATION MOISTURE-INDICATING METHODS AND ARTICLES 3M INNOVATIVE PROPERTIES COMPANY 2016-06-30 US disclosed
CN-1222542-C Catalyst solution for alpha-olefin polymerization BASF AG (DE) 2005-10-12 CN disclosed
CN-1604914-A Catalyst solid comprising pyrogenic silica for olefin polymerization BASELL POLYOLEFINE GMBH (DE) 2005-04-06 CN disclosed
CN-1110366-C Non-pyrophoric solids BASF AG (DE) 2003-06-04 CN disclosed
CN-1416435-A Catalyst for vinyl compound polymerization and process for producing vinyl polymer IDEMITSU PETROCHEMICAL CO (JP) 2003-05-07 CN disclosed
CN-1063763-C Olefin polymer composition MITSUI PETROCHEMICAL INC (JP) 2001-03-28 CN disclosed
CN-1255144-A Catalyst solution for polymerization of 'alpha'-olefines BASF AG (DE) 2000-05-31 CN disclosed
CN-1251057-A Non self-igniting solid BASF AG (DE) 2000-04-19 CN disclosed
CN-1069279-A Olefin polymer compositions MITUSI PETROCHEMICAL INC LTD (JP) 1993-02-24 CN disclosed
EP-0486393-A1 Sol-gel deposition process for thin layers by ultrasonic spraying CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1992-05-20 EP disclosed