SCHEMBL297260

SCHEMBL297260

CC(c1ccccc1)[SiH](Cl)Cl

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.46
TSHR P16473 1/20 0.46
TAAR1 Q96RJ0 4/20 0.42
ADRA2A P08913 1/20 0.41
ADRA2C P18825 1/20 0.41
CYP2D6 P10635 1/20 0.41
LMNA P02545 1/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 1/20 0.41
NOS2 P35228 1/20 0.40
SRC P12931 1/20 0.40
ALDH1A1 P00352 1/20 0.39
F2 P00734 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764960 0.74 TAAR1 (0.44) DPP4TSHRTAAR1ADRA2AADRA2C
SCHEMBL2686473 0.74 TSHR (0.48) DPP4TSHRTAAR1CYP2D6LMNA
SCHEMBL28772261 0.74 TAAR1 (0.44) DPP4TSHRTAAR1ADRA2AADRA2C
SCHEMBL18662195 0.74 HRH1 (0.46) TSHRTAAR1ADRA2ACYP2D6LMNA
SCHEMBL11727695 0.72 ADRA2C (0.46) TSHRTAAR1ADRA2AADRA2CCYP2D6
SCHEMBL22283511 0.72 TAAR1 (0.42) DPP4TAAR1ADRA2AADRA2CCYP2D6
SCHEMBL702838 0.72 TAAR1 (0.42) DPP4TSHRTAAR1ADRA2AADRA2C
SCHEMBL705957 0.72 TAAR1 (0.42) DPP4TSHRTAAR1ADRA2AADRA2C
SCHEMBL2103006 0.72 TSHR (0.52) DPP4TSHRTAAR1CYP2D6LMNA
SCHEMBL37100 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114130212-B Method for preparing separation membrane by using small molecular monomers 天津工业大学 2025-02-21 CN claimed
CN-114130212-A Method for preparing separation membrane by using small molecule monomer 天津工业大学 2022-03-04 CN claimed
CN-105348513-B A kind of Industrialized synthesis method of cladodification high intensity polysulfone resin 广东优巨先进材料研究有限公司 2017-12-26 CN claimed
US-20130153263-A1 INORGANIC NANOFILLER, PARTIAL DISCHARGE RESISTANT ENAMELED WIRE INCLUDING THE SAME, AND PREPARING METHOD OF THE ENAMELED WIRE SEJONG UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION (KR) 2013-06-20 US claimed
EP-2287231-B1 Ulltraviolet transmissive polyhedral silsesquioxane polymers PANASONIC CORP (JP) 2012-06-06 EP claimed
US-20110251357-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS PANASONIC ELECTRIC WORKS CO., LTD. 2011-10-13 US claimed
EP-2287231-A2 Ulltraviolet transmissive polyhedral silesquioxane polymers Panasonic Electric Works Co., Ltd. (JP) 2011-02-23 EP claimed
JP-2008523165-A 2008-07-03 JP claimed
CN-101098911-A Ultraviolet transmissive polyhedral silsequioxane polymers MATSUSHITA ELECTRIC WORKS LTD (JP) 2008-01-02 CN claimed
EP-1546250-B1 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING (US) 2007-12-19 EP claimed
EP-1833880-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS Matsushita Electric Works, Ltd. (JP) 2007-09-19 EP claimed
CN-1305948-C Organosilicon compounds and blends for treating silica DOW CORNING (US) 2007-03-21 CN claimed
WO-2006062219-A1 ULTRAVIOLET TRANSMISSIVE POLYHEDRAL SILSESQUIOXANE POLYMERS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 2006-06-15 WO claimed
US-20060122351-A1 Ultraviolet transmissive polyhedral silsesquioxane polymers PANASONIC ELECTRIC WORKS CO., LTD. (JP) 2006-06-08 US claimed
CN-1681880-A Organosilicon compounds and blends for treating silica DOW CORNING (US) 2005-10-12 CN claimed
EP-1546250-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA Dow Corning Corporation (US) 2005-06-29 EP claimed
WO-2004024812-A2 ORGANOSILICON COMPOUNDS AND BLENDS FOR TREATING SILICA DOW CORNING CORPORATION (US) 2004-03-25 WO claimed
US-6046293-A Solid-liquid phase interfacial polymerization UNIVERSITY OF SOUTH AUSTRALIA (AU) 2000-04-04 US claimed
EP-0799851-A2 Preparation of polyorganosilloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-10-08 EP claimed
US-5629401-A Preparation of polyorganosiloxanes by interfacial polymerization DOW CORNING CORPORATION (US) 1997-05-13 US claimed