Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063154 | 0.72 | OPRM1 (0.42) | GRIA1GRIA2GRIA3GRIA4OPRM1 | |
| SCHEMBL10063160 | 0.72 | OPRM1 (0.42) | OPRM1OPRL1OPRK1PARP2PARP3 | |
| SCHEMBL3380254 | 0.68 | OXTR (0.41) | OPRM1OPRL1HTR2CHTR2B | |
| SCHEMBL10062766 | 0.68 | OPRM1 (0.43) | OPRM1OPRL1OPRK1HTR2CHTR2B | |
| SCHEMBL181875 | 0.68 | OPRM1 (0.36) | GRIA1GRIA2GRIA3GRIA4OPRM1 | |
| SCHEMBL3381685 | 0.68 | OXTR (0.41) | HTR2CHTR2B | |
| SCHEMBL5546064 | 0.68 | CCR3 (0.38) | GRIA1GRIA2GRIA3GRIA4OPRM1 | |
| SCHEMBL7414811 | 0.68 | HTR2C (0.48) | OPRM1OPRL1OPRK1HTR2CHTR2B | |
| SCHEMBL20230166 | 0.67 | IDO1 (0.37) | PARP2PARP3HTR2CHTR2BCDK9 | |
| SCHEMBL15202948 | 0.65 | HTR2C (0.42) | GRIA1GRIA2GRIA3GRIA4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023229375-A1 | HETEROCYCLIC COMPOUND AS DIACYLGLYCEROL KINASE INHIBITOR AND USE THEREOF | 주식회사 엘지화학 | 2023-11-30 | — | — | WO | disclosed |