Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13100468 | 0.82 | — | — | |
| SCHEMBL15625950 | 0.79 | — | — | |
| SCHEMBL10112133 | 0.78 | CA12 (0.32) | — | |
| SCHEMBL15202723 | 0.74 | TP53 (0.34) | VCAM1 | |
| SCHEMBL13379960 | 0.74 | VCAM1 (0.33) | VCAM1 | |
| SCHEMBL777525 | 0.74 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL25477051 | 0.72 | TP53 (0.33) | VCAM1 | |
| SCHEMBL16732570 | 0.72 | CA2 (0.40) | VCAM1 | |
| SCHEMBL13301125 | 0.72 | — | — | |
| SCHEMBL25927506 | 0.69 | ALOX5 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381180-A1 | SMALL MOLECULE MODULATORS OF KSR-BOUND MEK | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381180-A1 | SMALL MOLECULE MODULATORS OF KSR-BOUND MEK | KSR1, KSR2, BRAF | VCAM1 4405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.