SCHEMBL2687240

SCHEMBL2687240

CCCCCOCC1(C(=O)c2ccccc2)c2ccccc2-c2ccccc21

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 1/20 0.41
RECQL P46063 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
PDK2 Q15119 2/20 0.40
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
MTTP P55157 1/20 0.39
CNR2 P34972 1/20 0.39
PTPN11 Q06124 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2687866 0.96 MTTP (0.42) CYP2C9CYP2C19NPSR1PDK2CES2
SCHEMBL2689135 0.91 LMNA (0.44) KMT2ATDP1PDK2MAPK1MTTP
SCHEMBL2688297 0.85 PDK2 (0.42) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2688828 0.85 THRB (0.39) MEN1KMT2ATDP1PDK2TSHR
SCHEMBL2465373 0.84 PDK2 (0.41) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2687380 0.83 PDK2 (0.41) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2686335 0.83 PDK2 (0.41) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2689532 0.83 PDK2 (0.41) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2685996 0.82 PDK2 (0.42) CYP2C9CYP2C19MEN1RECQLKMT2A
SCHEMBL2687530 0.82 PDK2 (0.42) CYP2C9CYP2C19MEN1RECQLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
CN-104053682-A High activity catalyst component for olefin polymerization and method of using the same BASF SE 2014-09-17 CN claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
CN-107207657-B Process for preparing spherical polymerization catalyst components for olefin polymerization 格雷斯公司 2020-03-03 CN disclosed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed