Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 18/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 17/20 | 0.48 |
| ▸ | CDK2 | P24941 | 10/20 | 0.48 |
| ▸ | CDK4 | P11802 | 8/20 | 0.48 |
| ▸ | CCND1 | P24385 | 8/20 | 0.48 |
| ▸ | CDK7 | P50613 | 8/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.48 |
| ▸ | CCNA1 | P78396 | 7/20 | 0.48 |
| ▸ | CDK3 | Q00526 | 7/20 | 0.48 |
| ▸ | CCNH | P51946 | 7/20 | 0.48 |
| ▸ | CDK1 | P06493 | 6/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.48 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.48 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.40 |
| ▸ | CDK14 | O94921 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26872826 | 0.96 | CDK9 (0.50) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26872838 | 0.84 | CDK9 (0.66) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26872817 | 0.83 | RAB9A (0.46) | CDK9CCNT1CDK2 | |
| SCHEMBL26871796 | 0.83 | CDK9 (0.48) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26872897 | 0.81 | CDK9 (0.62) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26873415 | 0.78 | CDK9 (0.49) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26871658 | 0.77 | CDK9 (0.65) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26871568 | 0.75 | CDK9 (0.62) | CDK9CCNT1CDK2CDK4CCND1 | |
| SCHEMBL26871139 | 0.75 | KDM4E (0.34) | — | |
| SCHEMBL21946097 | 0.74 | CDK9 (0.67) | CDK9CCNT1CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |