Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.34 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26871792 | 0.87 | CSNK2B (0.46) | CSNK2BRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26873608 | 0.86 | CDK9 (0.48) | CCNT1CDK9CDK2MAPKAPK2 | |
| SCHEMBL26872849 | 0.84 | CSNK2B (0.45) | CSNK2BRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26871783 | 0.78 | CDK9 (0.56) | CCNT1CDK9CDK2 | |
| SCHEMBL26871243 | 0.75 | KDM4E (0.33) | RAB9AKDM4EMAPT | |
| SCHEMBL26871796 | 0.74 | CDK9 (0.48) | CCNT1CDK9CDK2 | |
| SCHEMBL26873560 | 0.73 | CDK9 (0.63) | CCNT1CDK9CDK2GSK3BMAPKAPK2 | |
| SCHEMBL26873489 | 0.71 | CSNK2B (0.44) | CSNK2BRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26872817 | 0.71 | RAB9A (0.46) | CSNK2BRAB9ANPC1MEN1KMT2A | |
| SCHEMBL26869154 | 0.69 | KDM4E (0.34) | RAB9ANPC1CDK2GSK3BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4282868-A1 | SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE-7-AMINE DERIVATIVE, AND COMPOSITIONS AND MEDICAL USE THEREOF | Shanghai Haiyan Pharmaceutical Technology Co., Ltd (CN) | 2023-11-29 | — | — | EP | disclosed |