⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23823081 | 0.61 | — | — | |
| SCHEMBL15473505 | 0.58 | — | — | |
| SCHEMBL203914 | 0.58 | DYRK1A (0.34) | — | |
| SCHEMBL20126953 | 0.56 | ALDH1A1 (0.32) | — | |
| SCHEMBL20126955 | 0.56 | ALDH1A1 (0.32) | — | |
| SCHEMBL24595784 | 0.56 | HDAC3 (0.31) | — | |
| SCHEMBL18775167 | 0.55 | MAPT (0.33) | — | |
| SCHEMBL24595789 | 0.55 | GPR35 (0.34) | — | |
| SCHEMBL24344877 | 0.55 | MAPT (0.40) | — | |
| SCHEMBL24344563 | 0.55 | CYP2A6 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365541-A1 | INHIBITOR OF ENHANCER OF ZESTE HOMOLOGUE 2, AND USE THEREOF | XIZANG HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |