SCHEMBL203914

SCHEMBL203914

Cc1c2ccsc2c(C)c2ccsc12

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.34
MAPT P10636 4/20 0.34
KDM4E B2RXH2 3/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.34
TERT O14746 1/20 0.31
NPC1 O15118 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ADORA2A P29274 2/20 0.31
ADORA1 P30542 2/20 0.31
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18775167 0.89 MAPT (0.33) DYRK1AMAPTKDM4EALDH1A1GAA
SCHEMBL2589556 0.88 TSHR (0.38) MAPTKDM4EALDH1A1GAAHTT
SCHEMBL12036433 0.87 MAPT (0.32) DYRK1AMAPTKDM4EALDH1A1GAA
SCHEMBL20371351 0.86
SCHEMBL15277885 0.86 GPR35 (0.32) MAPTALDH1A1GAAHTTL3MBTL1
SCHEMBL12036432 0.85 MAPT (0.31) DYRK1AMAPTKDM4EALDH1A1GAA
SCHEMBL13262294 0.82 ADORA2A (0.34) MAPTADORA2AADORA1
SCHEMBL15281125 0.82 MAPT (0.34) DYRK1AMAPTKDM4EALDH1A1GAA
SCHEMBL15447923 0.78 ADORA3 (0.32) ADORA2AADORA1
SCHEMBL10733659 0.78 CYP1A2 (0.35) MAPTKDM4EALDH1A1GAATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230227475-A1 Asymmetric Fused Aromatic Ring Derivative Containing Sulfonyl Group, Use Thereof, Hydrogen Production Device and Optoelectronic Component NATIONAL TSING HUA UNIVERSITY (TW) 2023-07-20 US disclosed
WO-2023106404-A1 POLYMER COMPOUND, ORGANIC SEMICONDUCTOR MATERIAL, AND ORGANIC ELECTRONIC DEVICE 国立大学法人大阪大学 2023-06-15 WO disclosed
WO-2022090522-A1 POLYMER CAMBRIDGE DISPLAY TECHNOLOGY LTD (GB) 2022-05-05 WO disclosed
EP-3626716-A1 ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2020-03-25 EP disclosed
US-20190036029-A1 ORGANIC THIN FILM TRANSISTOR ELEMENT, ORGANIC SEMICONDUCTOR FILM-FORMING COMPOSITION, METHOD OF FORMING ORGANIC SEMICONDUCTOR FILM, AND ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2019-01-31 US disclosed
EP-3346504-A1 ORGANIC THIN-FILM TRANSISTOR, ORGANIC THIN-FILM TRANSISTOR MANUFACTURING METHOD, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, AND ORGANIC SEMICONDUCTOR FILM MANUFACTURING METHOD FUJIFILM Corporation (JP) 2018-07-11 EP disclosed
US-9981955-B2 Antiviral compounds GILEAD PHARMASSET LLC (US) 2018-05-29 US disclosed
US-9981955-B2 Antiviral compounds GILEAD PHARMASSET LLC (US) 2018-05-29 US disclosed
US-20180145258-A1 ORGANIC SEMICONDUCTOR ELEMENT, COMPOUND, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM, AND MANUFACTURING METHOD THEREOF FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed
US-20180145259-A1 ORGANIC SEMICONDUCTOR ELEMENT, COMPOUND, ORGANIC SEMICONDUCTOR COMPOSITION, AND METHOD OF MANUFACTURING ORGANIC SEMICONDUCTOR FILM FUJIFILM CORPORATION (JP) 2018-05-24 US disclosed
US-20110086994-A1 METHODS FOR PREPARING BENZODITHIOPHENES XEROX CORPORATION (US) 2011-04-14 US disclosed
WO-2011028827-A2 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. (US) 2011-03-10 WO disclosed
WO-2011028827-A2 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. (US) 2011-03-10 WO disclosed
WO-2011028829-A2 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED AND DIKETOPYRROLOPYRROLE-BASED POLYMERS PLEXTRONICS, INC. (US) 2011-03-10 WO disclosed
US-20100310512-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2010-12-09 US disclosed
US-20100310512-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2010-12-09 US disclosed
US-20100310512-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2010-12-09 US disclosed
US-20100307594-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2010-12-09 US disclosed
WO-2010132601-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-11-18 WO disclosed
WO-2010132601-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-11-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230227475-A1 Asymmetric Fused Aromatic Ring Derivative Containing Sulfonyl Group, Use Thereof, Hydrogen Production Device and Optoelectronic Component AHR, STS, HAT1 DYRK1A 1818/4885MAPT 4454/4885KDM4E 1870/4885
US-20110086994-A1 METHODS FOR PREPARING BENZODITHIOPHENES TST, TPST2, MPST DYRK1A 1791/4885MAPT 847/4885KDM4E 312/4885
US-20100310512-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, ZC3HAV1 DYRK1A 4823/4885MAPT 2923/4885KDM4E 2496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.