Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040061 | 1.00 | SMPD1 (0.32) | SMPD1MAPT | |
| SCHEMBL14975760 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL4549519 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL6815629 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL19227801 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL3630351 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL4549513 | 0.98 | FGF1 (0.32) | SMPD1 | |
| SCHEMBL4549509 | 0.98 | FGF1 (0.32) | SMPD1 | |
| Bromide SCHEMBL28927555 | 0.96 | FGF1 (0.34) | SMPD1 | |
| SCHEMBL8158571 | 0.88 | OGA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365608-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | JANSSEN BIOPHARMA, LLC | 2023-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365608-A1 | ANTIVIRAL NUCLEOSIDES AND DERIVATIVES THEREOF | PNP, NUDT1, ADAR | SMPD1 820/4885MAPT 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.