Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.70 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.68 |
| ▸ | MMP3 | P08254 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | SMO | Q99835 | 1/20 | 0.55 |
| ▸ | PLG | P00747 | 2/20 | 0.55 |
| ▸ | KLK1 | P06870 | 2/20 | 0.55 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26889400 | 0.92 | DEGS1 (0.68) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26886081 | 0.91 | ALDH1A1 (0.68) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL31150345 | 0.89 | DEGS1 (0.78) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL368228 | 0.89 | DEGS1 (0.78) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29519104 | 0.88 | DEGS1 (1.00) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7890743 | 0.88 | DEGS1 (1.00) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL26886085 | 0.87 | RAB9A (0.62) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8133663 | 0.87 | RAB9A (1.00) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL677505 | 0.87 | DEGS1 (0.74) | DEGS1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7835842 | 0.87 | DEGS1 (0.74) | DEGS1NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | UNIVERSITY OF MIAMI | 2023-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381159-A1 | SMALL MOLECULE INHIBITORS OF CORONAVIRUS ATTACHMENT AND ENTRY, METHODS AND USES THEREOF | ACE2, ACE, SARS1 | DEGS1 4754/4885NPC1 72/4885RAB9A 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.