Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127556 | 0.87 | ALDH1A1 (0.51) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL24709383 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL27331967 | 0.84 | ALDH1A1 (0.47) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL31646761 | 0.82 | ALDH1A1 (0.47) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL29300492 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL24596998 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL15354487 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL20610685 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1SIGMAR1HRH3SMN1; SMN2 | |
| SCHEMBL29300493 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E | |
| SCHEMBL24709151 | 0.81 | ALDH1A1 (0.49) | ALDH1A1TDP1SIGMAR1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023219952-A1 | MELANOCORTIN TYPE 2 RECEPTOR (MC2R) TARGETED THERAPEUTICS AND USES THEREOF | RADIONETICS ONCOLOGY, INC. (US) | 2023-11-16 | — | — | WO | disclosed |