Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666981 | 0.82 | MAPT (0.39) | TDP1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL14883530 | 0.79 | MAPT (0.40) | WDR5TDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL8667128 | 0.77 | CYP1A2 (0.40) | TDP1ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL14886295 | 0.74 | CYP2A6 (0.42) | WDR5TDP1ALDH1A1HSD17B10TSHR | |
| SCHEMBL8666425 | 0.73 | POLB (0.37) | TDP1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL8668404 | 0.73 | CYP2A6 (0.43) | TDP1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL8666337 | 0.73 | HPRT1 (0.36) | TDP1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL8665969 | 0.73 | CYP2A6 (0.43) | TDP1ALDH1A1HSD17B10TSHRCYP2A6 | |
| SCHEMBL8665808 | 0.72 | CYP1A2 (0.45) | ALDH1A1HSD17B10TSHRCYP2A6RECQL | |
| SCHEMBL8665295 | 0.72 | CYP2A6 (0.45) | ALDH1A1CYP2A6MAPTLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748629-B2 | Photochromic material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8748629-B2 | Photochromic material | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20130102775-A1 | PHOTOCHROMIC MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20130102775-A1 | PHOTOCHROMIC MATERIAL | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2013-04-25 | — | — | US | disclosed |
| WO-2012005354-A1 | PHOTOCHROMIC MATERIAL | 三菱瓦斯化学株式会社 (JP) | 2012-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102775-A1 | PHOTOCHROMIC MATERIAL | RB1, BRD4, H1-4 | WDR5 364/4885TDP1 3137/4885ALDH1A1 586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.