Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666425 | 0.81 | POLB (0.37) | CYP2A6CYP1A2TSHRALDH1A1MEN1 | |
| SCHEMBL8666337 | 0.81 | HPRT1 (0.36) | CYP2A6CYP1A2TSHRALDH1A1MEN1 | |
| SCHEMBL8665239 | 0.80 | MAPT (0.47) | CYP1A2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8666981 | 0.76 | MAPT (0.39) | CYP2A6CYP1A2TSHRALDH1A1MEN1 | |
| SCHEMBL2689653 | 0.73 | WDR5 (0.37) | CYP2A6CYP1A2TSHRALDH1A1HSD17B10 | |
| SCHEMBL8665808 | 0.73 | CYP1A2 (0.45) | CYP2A6CYP1A2TSHRALDH1A1MEN1 | |
| SCHEMBL2494354 | 0.73 | PSMB5 (0.40) | CYP2A6CYP1A2TSHRALDH1A1MEN1 | |
| SCHEMBL8663516 | 0.71 | MAPT (0.38) | CYP2A6CYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL81799 | 0.68 | ALDH1A1 (0.38) | TSHRALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL23654621 | 0.68 | L3MBTL1 (0.52) | CYP2A6CYP1A2TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |