Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665808 | 0.79 | CYP1A2 (0.45) | CYP2A6CYP1A2KMT2AKDM4EALDH1A1 | |
| SCHEMBL82274 | 0.78 | TAAR1 (0.40) | CYP2A6CYP1A2KMT2AATMKDM4E | |
| SCHEMBL80380 | 0.76 | CHRM1 (0.41) | CYP1A2KMT2ALMNAALDH1A1HTT | |
| SCHEMBL8666867 | 0.76 | IDO1 (0.42) | LMNAMAPT | |
| SCHEMBL8666981 | 0.75 | MAPT (0.39) | CYP2A6CYP1A2KMT2AATMKDM4E | |
| SCHEMBL8666379 | 0.75 | CYP2A6 (0.34) | CYP2A6CYP1A2KMT2AKDM4ELMNA | |
| SCHEMBL356036 | 0.74 | CYP2A6 (0.36) | CYP2A6CYP1A2KMT2ALMNAMAPT | |
| SCHEMBL8668404 | 0.73 | CYP2A6 (0.43) | CYP2A6CYP1A2KMT2AATMKDM4E | |
| SCHEMBL2689653 | 0.72 | WDR5 (0.37) | CYP2A6CYP1A2ATMKDM4ELMNA | |
| SCHEMBL18037939 | 0.72 | CYP1A2 (0.45) | CYP2A6CYP1A2KMT2AATMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792589-A | ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1998-08-11 | — | — | US | disclosed |