SCHEMBL8665808

SCHEMBL8665808

Cc1ccc(C2(C3(c4ccc(C)c5ccccc45)N=C(c4ccccc4)C(c4ccccc4)=N3)N=C(c3ccccc3)C(c3ccccc3)=N2)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.45
CCR2 P41597 1/20 0.36
CYP2A6 P11509 2/20 0.35
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
TNKS O95271 1/20 0.33
PARP1 P09874 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
BACE1 P56817 1/20 0.33
PSMD14 O00487 1/20 0.32
COPS5 Q92905 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTT P42858 1/20 0.32
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
HK2 P52789 1/20 0.31
POLB P06746 1/20 0.31
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8665295 0.79 CYP2A6 (0.45) CYP1A2CYP2A6ALDH1A1HTTKDM4E
SCHEMBL8666867 0.79 IDO1 (0.42) L3MBTL1TNKSTNKS2HPGD
SCHEMBL81799 0.78 ALDH1A1 (0.38) ALDH1A1L3MBTL1TNKSPARP1TNKS2
SCHEMBL490787 0.76 KDM4E (0.39) ALDH1A1L3MBTL1HTTKDM4EHPGD
SCHEMBL8666981 0.75 MAPT (0.39) CYP1A2CYP2A6ALDH1A1L3MBTL1SLC6A2
SCHEMBL8665969 0.73 CYP2A6 (0.43) CYP1A2CYP2A6ALDH1A1L3MBTL1TNKS
SCHEMBL2689653 0.72 WDR5 (0.37) CYP1A2CYP2A6ALDH1A1L3MBTL1SLC6A2
SCHEMBL11594968 0.72 ALDH1A1 (0.34) CYP1A2ALDH1A1L3MBTL1HTTHPGD
SCHEMBL8667128 0.70 CYP1A2 (0.40) CYP1A2ALDH1A1L3MBTL1KDM4EHPGD
SCHEMBL8663516 0.70 MAPT (0.38) CYP1A2CYP2A6ALDH1A1TNKSPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5792589-A ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-08-11 US disclosed