Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390053 | 0.91 | ELANE (0.58) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL777803 | 0.86 | ELANE (0.62) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL10726589 | 0.85 | MAPT (0.55) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2688206 | 0.84 | KMT2A (0.70) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL5630152 | 0.84 | KMT2A (0.60) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13133117 | 0.83 | KMT2A (0.56) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9607439 | 0.83 | KMT2A (0.74) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6251985 | 0.80 | ALDH1A1 (0.57) | KMT2ARAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13410392 | 0.79 | LMNA (0.77) | KMT2AMAPTALDH1A1GAAELANE | |
| SCHEMBL684696 | 0.79 | SAE1 (0.59) | KMT2ASMN1; SMN2MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567281-B2 | 4-acylaralkylphenols and derivatives thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-02-14 | — | — | US | disclosed |
| US-9090547-B2 | Method for producing trisphenols and monoester-substituted products thereof, and 4-acylaralkylphenol derivatives | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221680-A1 | 4-Acylaralkylphenols and Derivatives Thereof | UGT1A7, CYP19A1, UGT2B7 | KMT2A 2968/4885RAB9A 3620/4885SMN1; SMN2 4304/4885 |
| US-20120108853-A1 | METHOD FOR PRODUCING TRISPHENOLS AND MONOESTER-SUBSTITUTED PRODUCTS THEREOF, AND 4-ACYLARALKYLPHENOL DERIVATIVES | CYP19A1, MTTP, CYP4X1 | KMT2A 2276/4885RAB9A 4257/4885SMN1; SMN2 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.