Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068492 | 0.97 | — | — | |
| SCHEMBL2248281 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL9172531 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL9172521 | 0.65 | — | — | |
| Iodide SCHEMBL5013840 | 0.63 | ALDH1A1 (0.32) | — | |
| SCHEMBL15871767 | 0.63 | TSHR (0.43) | — | |
| SCHEMBL31534793 | 0.61 | — | — | |
| Hydrochloric Acid SCHEMBL2266459 | 0.61 | — | — | |
| SCHEMBL21318389 | 0.60 | — | — | |
| SCHEMBL12091767 | 0.60 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168766-B2 | Process of making 2-deoxy-2,2-difluoro-D-ribofuranosyl nucleosides and intermediates therefor | ScnioPharm Taiwan Ltd. (TW) | 2012-05-01 | — | — | US | disclosed |
| US-20100056771-A1 | Process of Making 2-Deoxy-2,2-Difluoro-D-Ribofuranosyl Nucleosides and Intermediates Therefor | SCINOPHARM TAIWAN LTD. (TW) | 2010-03-04 | — | — | US | disclosed |
| EP-0650478-A1 | METHOD OF FORMING N-PROTECTED AMINO ACID THIOHYDANTOINS | THE PERKIN-ELMER CORPORATION (US) | 1995-05-03 | — | — | EP | disclosed |
| US-5304497-A | Method of forming N-protected amino acid thiohydantoins | APPLIED BIOSYSTEMS, INC. (US) | 1994-04-19 | — | — | US | disclosed |
| WO-1994002468-A1 | METHOD OF FORMING N-PROTECTED AMINO ACID THIOHYDANTOINS | APPLIED BIOSYSTEMS, INC. (US) | 1994-02-03 | — | — | WO | disclosed |