Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137664 | 0.97 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10 | |
| Bromide SCHEMBL15361375 | 0.95 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10 | |
| Hydrochloric Acid SCHEMBL15361726 | 0.95 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10 | |
| Water SCHEMBL15361687 | 0.95 | ALDH1A1 (0.32) | ALDH1A1LMNAHSD17B10 | |
| SCHEMBL10479087 | 0.89 | — | — | |
| Iodide SCHEMBL5015161 | 0.81 | — | — | |
| SCHEMBL5817406 | 0.78 | HCAR2 (0.30) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL1138043 | 0.78 | — | — | |
| SCHEMBL5814573 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNA | |
| SCHEMBL5286378 | 0.72 | NAAA (0.44) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465834-B2 | Bis(dimethylamino)propylthiomethylium bis(trifluoromethanesulfonyl)imide; bis(dimethylamino)ethoxymethylium bis(trifluoromethanesulfonyl)imide; stable liquid state even at low temperatures; good conductivity | KANTO DENKA KOGYO CO., LTD. (JP) | 2008-12-16 | — | — | US | disclosed |
| US-20050136332-A1 | Bis(dimethylamino)propylthiomethylium bis(trifluoromethanesulfonyl)imide; bis(dimethylamino)ethoxymethylium bis(trifluoromethanesulfonyl)imide; stable liquid state even at low temperatures; good conductivity | KANTO DENKA KOGYO CO., LTD. (JP) | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050136332-A1 | Bis(dimethylamino)propylthiomethylium bis(trifluoromethanesulfonyl)imide; bis(dimethylamino)ethoxymethylium bis(trifluoromethanesulfonyl)imide; stable liquid state even at low temperatures; good conductivity | ZYX, KCNH2, KCNH3 | ALDH1A1 3681/4885LMNA 314/4885HSD17B10 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.