Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GPR139 | Q6DWJ6 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.37 |
| ▸ | CDC42 | P60953 | 1/20 | 0.37 |
| ▸ | RAC1 | P63000 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26907899 | 0.88 | BRD4 (0.38) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| SCHEMBL29069567 | 0.80 | ALDH1A1 (0.46) | MAPTSMN1; SMN2POLBLMNAHPGD | |
| SCHEMBL27114611 | 0.78 | CA1 (0.57) | MAPTSMN1; SMN2POLBGPR139L3MBTL1 | |
| SCHEMBL29769966 | 0.76 | CA1 (0.43) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| Hydrochloric Acid SCHEMBL26907885 | 0.76 | KDM4E (0.42) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| Hydrochloric Acid SCHEMBL29770007 | 0.76 | KDM4E (0.42) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| Hydrochloric Acid SCHEMBL27115889 | 0.76 | KDM4E (0.42) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| SCHEMBL29069555 | 0.75 | GPR139 (0.41) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| SCHEMBL30547567 | 0.75 | GPR139 (0.41) | MAPTSMN1; SMN2POLBLMNAGPR139 | |
| SCHEMBL26907981 | 0.75 | GPR139 (0.41) | MAPTSMN1; SMN2POLBLMNAGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | claimed |
| EP-4286374-A1 | NOVEL BENZOTRIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE, AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-12-06 | — | — | EP | disclosed |
| CN-116724026-A | Novel benzotriazole derivatives having inhibitory activity against dinucleotide pyrophosphatase-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-09-08 | — | — | CN | disclosed |