Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 5/20 | 0.40 |
| ▸ | PPARA | Q07869 | 5/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18724303 | 0.87 | SLC7A5 (0.50) | LDHASLC7A5CA12CA1CA2 | |
| SCHEMBL2617129 | 0.86 | SLC7A5 (0.71) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL21690434 | 0.86 | SLC7A5 (0.71) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL2617199 | 0.86 | SLC7A5 (0.71) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL15828913 | 0.85 | SLC7A5 (0.47) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL15876045 | 0.82 | ITGB3 (0.47) | SLC7A5PPARGPPARAPPARDITGB3 | |
| SCHEMBL4399614 | 0.82 | SLC7A5 (0.51) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL18873599 | 0.82 | SLC7A5 (0.45) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL2058743 | 0.82 | SLC7A5 (0.55) | SLC7A5CA12CA1CA2CA9 | |
| SCHEMBL7390262 | 0.81 | ACE (0.61) | PPARGPPARAPPARDITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168821-B2 | Cyclopropylacetic acid derivatives and use thereof | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-05-01 | — | — | US | disclosed |
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | BAYER HEALTHCARE AG (DE) | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286882-A1 | Cyclopropylacetic Acid Derivatives and Use Thereof | PCCA, PPP2CA, HMGCR | LDHA 622/4885SLC7A5 2188/4885CA12 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.