SCHEMBL26911069

SCHEMBL26911069

Cc1cc(Cl)cc(C(=O)NC(C)(C)C)c1NC(=O)c1cc(OCCF)nn1-c1ncccc1Cl

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ANO1 Q5XXA6 7/20 0.33
NTRK1 P04629 6/20 0.33
MALT1 Q9UDY8 2/20 0.33
DHODH Q02127 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
SMO Q99835 1/20 0.31
ACKR3 P25106 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15556113 0.94 ANO1 (0.34) ANO1NTRK1MALT1DHODHCNR1
SCHEMBL29370423 0.94 ANO1 (0.34) ANO1NTRK1MALT1DHODHCNR1
SCHEMBL29039009 0.87 ANO1 (0.35) ANO1NTRK1MALT1DHODHCNR1
SCHEMBL13998640 0.86 KMT2A (0.38) ANO1MALT1DHODH
SCHEMBL10028761 0.85 KDM4E (0.37) MALT1DHODH
SCHEMBL10028762 0.84 DHODH (0.43) ANO1MALT1DHODHCNR1CNR2
SCHEMBL21224067 0.84 MALT1 (0.35) ANO1MALT1DHODHSMO
SCHEMBL28502293 0.84 MALT1 (0.35) MALT1DHODHCNR2SMO
SCHEMBL30396821 0.84 MALT1 (0.35) ANO1MALT1DHODHSMO
SCHEMBL28504323 0.84 MALT1 (0.32) ANO1NTRK1MALT1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230389550-A1 HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 2023-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230389550-A1 HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES CYP4F3, TARS2, TH ANO1 4725/4885NTRK1 3003/4885MALT1 3624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.