Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.48 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 7/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30447006 | 1.00 | JAK3 (0.48) | JAK3MAP2K7AURKAGSK3BJAK1 | |
| SCHEMBL26911311 | 0.91 | BTK (0.52) | JAK3MAP2K7AURKAGSK3BTGM2 | |
| SCHEMBL30446993 | 0.91 | BTK (0.52) | JAK3MAP2K7AURKAGSK3BTGM2 | |
| SCHEMBL26911572 | 0.81 | BTK (0.42) | TGM2BTKEGFRALDH1A1NPSR1 | |
| SCHEMBL30377067 | 0.79 | NPSR1 (0.42) | ALDH1A1LMNANPSR1 | |
| SCHEMBL26911600 | 0.78 | L3MBTL1 (0.41) | ALDH1A1LMNANPSR1 | |
| SCHEMBL26911603 | 0.77 | NPSR1 (0.41) | JAK3ALDH1A1LMNANPSR1 | |
| SCHEMBL30446277 | 0.77 | BTK (0.61) | MAP2K7AURKATGM2BTKEGFR | |
| SCHEMBL26911085 | 0.77 | BTK (0.61) | MAP2K7AURKATGM2BTKEGFR | |
| SCHEMBL25235509 | 0.75 | TEAD1 (0.40) | TGM2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-12-07 | — | — | US | claimed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | claimed |
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| CN-115956080-A | Bicyclic compounds, compositions containing them and their use | 贝达药业股份有限公司 | 2023-04-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | CYP11B2, CYP11B1, CYP27A1 | JAK3 2637/4885MAP2K7 4106/4885AURKA 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.