SCHEMBL26914883

SCHEMBL26914883

CC(C)(C)OC(=O)N1Cc2ccc(Cl)nc2CC1C1(O)CC1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ABHD6 Q9BV23 1/20 0.40
▸ KMT2A Q03164 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ PTPN1 P18031 4/20 0.35
▸ ESR2 Q92731 1/20 0.35
▸ GRM5 P41594 1/20 0.35
▸ NR1H2 P55055 1/20 0.34
▸ HDAC8 Q9BY41 4/20 0.34
▸ LMNA P02545 1/20 0.33
▸ KDM1A O60341 2/20 0.33
▸ USP30 Q70CQ3 1/20 0.32
▸ DDB1 Q16531 1/20 0.32
▸ CRBN Q96SW2 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.32
▸ HSP90AB1 P08238 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26914874 0.84 NR1H2 (0.39) KMT2AMEN1PTPN1GRM5NR1H2
SCHEMBL29264471 0.83 ABHD6 (0.37) ABHD6
SCHEMBL24602686 0.81 MEN1 (0.43) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL24602685 0.81 ABHD6 (0.42) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL30685431 0.81 MEN1 (0.43) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL26914877 0.80 ABHD6 (0.41) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL31621607 0.80 ABHD6 (0.44) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL31621630 0.80 ABHD6 (0.44) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL26914843 0.80 MEN1 (0.47) ABHD6KMT2AMEN1PTPN1ESR2
SCHEMBL24602711 0.79 MEN1 (0.41) ABHD6KMT2AMEN1PTPN1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF SCINNOHUB PHARMACEUTICAL CO., LTD (CN) 2024-04-18 — — US disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
EP-4289850-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF Scinnohub Pharmaceutical Co., Ltd (CN) 2023-12-13 — — EP disclosed
CN-116848122-A Plasmin inhibitor, preparation method and application thereof 赛诺哈勃药业(成都)有限公司 2023-10-03 — — CN disclosed
WO-2022166845-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 赛诺哈勃药业(成都)有限公司 2022-08-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124443-A1 PLASMIN INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF F2, PLG, PLAT ABHD6 2535/4885KMT2A 2898/4885MEN1 726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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