SCHEMBL26915693

SCHEMBL26915693

O=CCc1cc2nccc(Cl)c2s1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 3/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29997769 0.80 KDM4E (0.32) USP7
SCHEMBL23666994 0.80 KDM4E (0.32) USP7
SCHEMBL1850156 0.79 USP7 (0.40) USP7
SCHEMBL25282439 0.79 LOXL2 (0.38) USP7
SCHEMBL25739758 0.79 USP7 (0.31) USP7
SCHEMBL23911563 0.76 MAPKAPK2 (0.34) USP7
SCHEMBL30496258 0.76 CYP2A6 (0.40)
SCHEMBL307422 0.76 CYP2A6 (0.40)
SCHEMBL5245172 0.75 CYP2A6 (0.41) USP7
SCHEMBL23911531 0.74 CYP1A2 (0.33) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4288442-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF Faxian Therapeutics, LLC (US) 2023-12-13 EP disclosed
WO-2022170198-A1 UBIQUITIN-SPECIFIC PROTEASE 7 (USP7) INHIBITORS AND USES THEREOF FAXIAN THERAPEUTICS, LLC (US) 2022-08-11 WO disclosed