Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 6/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121818 | 0.89 | ALDH1A1 (0.37) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL2581743 | 0.86 | ALDH1A1 (0.41) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL13551905 | 0.84 | ALDH1A1 (0.35) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL28521546 | 0.82 | ALOX15 (0.33) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL28530381 | 0.82 | ALDH1A1 (0.33) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL16862478 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL9809890 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL22203032 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL28991876 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDBLMCYP1A2CYP2C19 | |
| SCHEMBL557952 | 0.82 | ALDH1A1 (0.38) | ALDH1A1HPGDBLMCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133680-B2 | affinity substrate comprises polydimethylsiloxane stamp alternately peptide-terminated or antibody terminated; | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-03-13 | — | — | US | disclosed |
| US-7651662-B2 | Rubbed substrate surfaces; activation; uniform anchoring of liquid crystals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-01-26 | — | — | US | disclosed |