Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MMP14 | P50281 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | CASP6 | P55212 | 2/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15182269 | 0.93 | ERAP1 (0.46) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL12645032 | 0.79 | ERAP1 (0.44) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| Perchlorate SCHEMBL268534 | 0.73 | ERAP1 (0.42) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL7770227 | 0.71 | KDM4E (0.42) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| Perchlorate SCHEMBL269605 | 0.70 | ERAP1 (0.39) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| Perchlorate SCHEMBL268972 | 0.69 | ERAP1 (0.38) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL1049324 | 0.69 | ERAP1 (0.50) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19102582 | 0.68 | LMNA (0.51) | ERAP1KDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL21078420 | 0.68 | KCNH2 (0.33) | ALDH1A1L3MBTL1RAB9ANPC1ALOX15 | |
| SCHEMBL21078421 | 0.68 | ALDH1A1 (0.31) | ALDH1A1L3MBTL1RAB9ANPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9118019-B2 | Heterocyclic radical or diradical, the dimers, oligomers, polymers, dispiro compounds and polycycles thereof, the use thereof, organic semiconductive material and electronic or optoelectronic component | NOVALED AG (DE) | 2015-08-25 | — | — | US | disclosed |
| US-20120146012-A1 | Heterocyclic Radical or Diradical, The Dimers, Oligomers, Polymers, Dispiro Compounds and Polycycles Thereof, the Use Thereof, Organic Semiconductive Material and Electronic or Optoelectronic Component | NOVALED AG (DE) | 2012-06-14 | — | — | US | disclosed |
| US-8134146-B2 | Heterocyclic radical or diradical, the dimers, oligomers, polymers, dispiro compounds and polycycles thereof, the use thereof, organic semiconductive material and electronic or optoelectronic component | NOVALED AG (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20070252140-A1 | Heterocyclic Radical or Diradical, the Dimers, Oligomers, Polymers, Dispiro Compounds and Polycycles Thereof, the Use Thereof, Organic Semiconductive Material and Electronic or Optoelectronic Component | NOVALED AG (DE) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120146012-A1 | Heterocyclic Radical or Diradical, The Dimers, Oligomers, Polymers, Dispiro Compounds and Polycycles Thereof, the Use Thereof, Organic Semiconductive Material and Electronic or Optoelectronic Component | PPOX, SCO2, CCNO | ERAP1 4864/4885KDM4E 4796/4885MAPT 1283/4885 |
| US-20070252140-A1 | Heterocyclic Radical or Diradical, the Dimers, Oligomers, Polymers, Dispiro Compounds and Polycycles Thereof, the Use Thereof, Organic Semiconductive Material and Electronic or Optoelectronic Component | PPOX, SCO2, CCNO | ERAP1 4864/4885KDM4E 4802/4885MAPT 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.