Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8229692 | 0.87 | TDP1 (0.48) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL29509634 | 0.82 | HSPB1 (0.45) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL12480460 | 0.82 | HSPB1 (0.45) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL11693495 | 0.78 | TDP1 (0.67) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL9004049 | 0.75 | TDP1 (0.48) | TDP1ALDH1A1L3MBTL1RECQLSMN1; SMN2 | |
| SCHEMBL26921178 | 0.74 | ALDH1A1 (0.57) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL20797745 | 0.74 | ALDH1A1 (0.51) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL3010961 | 0.73 | TDP1 (0.61) | TDP1ALDH1A1HSPB1SMN1; SMN2TSHR | |
| SCHEMBL29231859 | 0.73 | ALDH1A1 (0.43) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 | |
| SCHEMBL14333927 | 0.72 | PDK1 (0.48) | TDP1ALDH1A1HSPB1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288433-A1 | NOVEL COMPOUNDS | Cerevance, Inc. (US) | 2023-12-13 | — | — | EP | disclosed |