SCHEMBL2692186

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23343817	0.85	TAAR1 (0.49)	PDK2HTR2AHTR2BHTR2CACP3
	SCHEMBL27957352	0.83	ESR1 (0.50)	PDK1PDK2PDK3PDK4PRKCA
	SCHEMBL2257	0.83	TAAR1 (0.60)	PRKCAPRKCDHTR2AHTR2BHTR2C
	SCHEMBL17805427	0.83	HTR2A (0.47)	HTR2AHTR2BHTR2CACP3TAAR1
	SCHEMBL30484278	0.83	IKBKB (0.50)	PDK1PDK2PDK3PDK4PRKCA
	SCHEMBL2600025	0.83	IKBKB (0.50)	PDK1PDK2PDK3PDK4PRKCA
	SCHEMBL17682238	0.83	PDK1 (0.50)	PDK1PDK2PDK3PDK4PRKCA
	Alcohol SCHEMBL29251271	0.82	HTR2A (0.56)	PRKCAPRKCDHTR2AHTR2BHTR2C
	SCHEMBL2636462	0.82	PDK1 (0.44)	PDK1PDK2PDK3PDK4PRKCA
	SCHEMBL27370336	0.82	TAAR1 (0.58)	PRKCAPRKCDHTR2AHTR2BHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.