Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR2B | P41595 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MIF | P14174 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2257 | 0.94 | TAAR1 (0.60) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL27370336 | 0.92 | TAAR1 (0.58) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL46757 | 0.84 | HTR2A (0.63) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL10269541 | 0.83 | PRKCI (0.53) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL2692186 | 0.82 | PDK1 (0.46) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| Ammonia Solution, Strong SCHEMBL266843 | 0.82 | HTR2A (0.61) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL29278401 | 0.81 | TAAR1 (0.61) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL30777700 | 0.81 | TAAR1 (0.61) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| Hydrochloric Acid SCHEMBL21272642 | 0.80 | IDO1 (0.59) | HTR2AHTR2BHTR2CPRKCAPRKCD | |
| SCHEMBL11195440 | 0.79 | PRKCA (0.50) | PRKCAPRKCDIDO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117844077-A | Corrosion-resistant rubber composite material and preparation method thereof | 江苏多肯新材料有限公司 | 2024-04-09 | — | — | CN | disclosed |