Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | LOX | P28300 | 1/20 | 0.58 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.58 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.53 |
| ▸ | HTR3B | O95264 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 1/20 | 0.53 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.53 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5610968 | 0.81 | LOXL2 (0.58) | LOXL2RECQLLOXLOXL3EPHX1 | |
| SCHEMBL27731807 | 0.77 | RECQL (0.62) | LOXL2RECQLLOXLOXL3EPHX1 | |
| SCHEMBL2371002 | 0.76 | GABRP (0.62) | LOXL2RECQLLOXLOXL3EPHX1 | |
| SCHEMBL29421806 | 0.76 | GABRP (0.62) | LOXL2RECQLLOXLOXL3EPHX1 | |
| SCHEMBL1886874 | 0.74 | RECQL (0.58) | LOXL2RECQLLOXLOXL3EPHX1 | |
| SCHEMBL451390 | 0.74 | — | — | |
| SCHEMBL2644628 | 0.74 | — | — | |
| SCHEMBL904475 | 0.74 | — | — | |
| SCHEMBL2496843 | 0.74 | LOXL2 (0.53) | LOXL2RECQLLOXLOXL3EPHX1 | |
| Hydrochloric Acid SCHEMBL18345926 | 0.72 | LOXL2 (0.96) | LOXL2RECQLLOXLOXL3EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4288436-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2023-12-13 | — | — | EP | disclosed |