Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 6/20 | 0.48 |
| ▸ | TRAP1 | Q12931 | 3/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30686900 | 0.81 | ABHD6 (0.54) | ABHD6SLC6A9DPP8DPP9DPP7 | |
| SCHEMBL26922821 | 0.81 | ABHD6 (0.54) | ABHD6SLC6A9DPP8DPP9DPP7 | |
| SCHEMBL16638014 | 0.80 | ABHD6 (0.61) | ABHD6TRAP1HSP90B1SLC6A9 | |
| SCHEMBL30772456 | 0.74 | TRAP1 (0.56) | ABHD6TRAP1HSP90B1DPP8DPP9 | |
| SCHEMBL497487 | 0.74 | TRAP1 (0.56) | ABHD6TRAP1HSP90B1DPP8DPP9 | |
| SCHEMBL7946982 | 0.73 | TRAP1 (0.52) | ABHD6TRAP1SLC6A9DPP8DPP9 | |
| SCHEMBL16637906 | 0.73 | TRAP1 (0.43) | ABHD6TRAP1HSP90B1 | |
| SCHEMBL4437645 | 0.71 | ABHD6 (0.57) | ABHD6TRAP1HSP90B1DPP8DPP9 | |
| SCHEMBL31504518 | 0.71 | AKR1C3 (0.42) | ABHD6TRAP1HSP90B1DPP8DPP9 | |
| SCHEMBL3469584 | 0.71 | TRAP1 (0.53) | TRAP1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240024-A1 | SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS | NIKANG THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |