Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 6/20 | 0.47 |
| ▸ | MGLL | Q99685 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23803972 | 0.92 | NLRP3 (0.40) | SMPD1MGLLHPGD | |
| SCHEMBL31092565 | 0.84 | MAPT (0.39) | — | |
| SCHEMBL17386167 | 0.83 | EGFR (0.43) | ALDH1A1HPGD | |
| SCHEMBL26688921 | 0.82 | KDM4E (0.40) | SMPD1MGLLALDH1A1HPGD | |
| SCHEMBL5899519 | 0.81 | MAPT (0.50) | MGLLALDH1A1HPGD | |
| SCHEMBL17429672 | 0.81 | UCHL1 (0.36) | ALDH1A1 | |
| SCHEMBL9565566 | 0.79 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPTPN11 | |
| SCHEMBL967401 | 0.79 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPTPN11 | |
| SCHEMBL9304902 | 0.79 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPTPN11 | |
| SCHEMBL24950547 | 0.79 | SMPD1 (0.67) | SMPD1MGLLALDH1A1HPGDPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023236924-A1 | BIPHENYL COMPOUND, PHARMACEUTICAL COMPOSITION, METHOD FOR PREPARING SAME, AND USE THEREOF | 朗捷睿(苏州)生物科技有限公司 | 2023-12-14 | — | — | WO | disclosed |