Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 5/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201375 | 1.00 | KLK7 (0.42) | KLK7GHSRSTSPARP1PTPN1 | |
| SCHEMBL201456 | 1.00 | KLK7 (0.42) | KLK7GHSRSTSPARP1PTPN1 | |
| SCHEMBL201376 | 1.00 | KLK7 (0.42) | KLK7GHSRSTSPARP1PTPN1 | |
| SCHEMBL201385 | 0.86 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19233879 | 0.84 | KLK7 (0.46) | KLK7PARP1ABCB1NR1H2NR1H3 | |
| SCHEMBL12478959 | 0.84 | KLK7 (0.46) | KLK7PARP1ABCB1NR1H2NR1H3 | |
| SCHEMBL16917854 | 0.84 | KLK7 (0.46) | KLK7PARP1ABCB1NR1H2NR1H3 | |
| SCHEMBL12480576 | 0.84 | KLK7 (0.46) | KLK7PARP1ABCB1NR1H2NR1H3 | |
| SCHEMBL13967442 | 0.84 | KLK7 (0.46) | KLK7PARP1ABCB1NR1H2NR1H3 | |
| SCHEMBL203307 | 0.83 | GHSR (0.41) | KLK7GHSRSTSPARP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088804-B2 | N-hydroxyamide derivatives possessing antibacterial activity | PFIZER INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100022605-A1 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. | 2010-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100022605-A1 | N-HYDROXYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | NAAA, HDHD5, HACL2 | KLK7 3987/4885GHSR 1457/4885STS 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.