Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.61 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.61 |
| ▸ | ITGAV | P06756 | 1/20 | 0.61 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.61 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.59 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.57 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.55 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26935045 | 0.93 | KRAS (0.58) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL26935074 | 0.91 | KLK5 (0.56) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL26935034 | 0.91 | ITGB3 (0.63) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL29666543 | 0.89 | PIN1 (0.58) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL29666555 | 0.88 | HDAC4 (0.57) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL29666550 | 0.87 | HDAC4 (0.62) | HDAC4KLKB1KRASHDAC1HDAC3 | |
| SCHEMBL29666795 | 0.86 | KRAS (0.56) | HDAC4PCSK9KLKB1KRASHDAC1 | |
| SCHEMBL26935065 | 0.85 | HDAC3 (0.60) | HDAC4PCSK9KLKB1KLK5HDAC1 | |
| SCHEMBL1371652 | 0.84 | ITGB3 (0.60) | ITGB3ITGB1ITGAVITGA5ITGB5 | |
| SCHEMBL26935070 | 0.84 | HDAC3 (0.58) | HDAC4PCSK9KLKB1KLK5HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399362-A1 | INTERLEUKIN-13 BINDING CYCLIC OLIGOPEPTIDES AND METHODS OF USE THEREOF | B.A.I. LABORATORIES, LLC | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399362-A1 | INTERLEUKIN-13 BINDING CYCLIC OLIGOPEPTIDES AND METHODS OF USE THEREOF | CXCL10, IL23R, CCL11 | ITGB3 727/4885ITGB1 1401/4885ITGAV 765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.