Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | MITF | O75030 | 1/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3272232 | 1.00 | MAPT (0.68) | MAPTHPGDALDH1A1SMN1; SMN2MITF | |
| SCHEMBL11388177 | 0.85 | NOX1 (0.91) | MAPTHPGDALDH1A1SMN1; SMN2NOX1 | |
| SCHEMBL11388174 | 0.85 | NOX1 (0.91) | MAPTHPGDALDH1A1SMN1; SMN2NOX1 | |
| SCHEMBL26935005 | 0.82 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2MITF | |
| SCHEMBL26915313 | 0.82 | MAPT (1.00) | MAPTHPGDALDH1A1SMN1; SMN2MITF | |
| SCHEMBL42159 | 0.81 | NOX1 (1.00) | MAPTHPGDALDH1A1SMN1; SMN2NOX1 | |
| SCHEMBL22874080 | 0.81 | NOX1 (1.00) | MAPTHPGDALDH1A1SMN1; SMN2NOX1 | |
| SCHEMBL42160 | 0.81 | NOX1 (1.00) | MAPTHPGDALDH1A1SMN1; SMN2NOX1 | |
| SCHEMBL29859752 | 0.80 | MAPT (0.72) | MAPTHPGDALDH1A1SMN1; SMN2MITF | |
| SCHEMBL26935144 | 0.80 | MAPT (0.72) | MAPTHPGDALDH1A1SMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289422-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kyushu University, National University Corporation (JP) | 2023-12-13 | — | — | EP | disclosed |