SCHEMBL3272232

SCHEMBL3272232

CC(C)c1ccc(C=NNc2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.68
HPGD P15428 4/20 0.68
ALDH1A1 P00352 3/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
MITF O75030 1/20 0.68
NOX1 Q9Y5S8 2/20 0.67
RAB9A P51151 6/20 0.62
GAA P10253 5/20 0.62
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.62
LMNA P02545 1/20 0.62
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
NPC1 O15118 5/20 0.50
KDM4E B2RXH2 4/20 0.50
POLB P06746 2/20 0.50
ALOX12 P18054 1/20 0.50
PKM P14618 1/20 0.48
MAPK1 P28482 1/20 0.46
ESRRG P62508 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26935149 1.00 MAPT (0.68) MAPTHPGDALDH1A1SMN1; SMN2MITF
SCHEMBL11388177 0.85 NOX1 (0.91) MAPTHPGDALDH1A1SMN1; SMN2NOX1
SCHEMBL11388174 0.85 NOX1 (0.91) MAPTHPGDALDH1A1SMN1; SMN2NOX1
SCHEMBL26935005 0.82 MAPT (1.00) MAPTHPGDALDH1A1SMN1; SMN2MITF
SCHEMBL26915313 0.82 MAPT (1.00) MAPTHPGDALDH1A1SMN1; SMN2MITF
SCHEMBL42159 0.81 NOX1 (1.00) MAPTHPGDALDH1A1SMN1; SMN2NOX1
SCHEMBL22874080 0.81 NOX1 (1.00) MAPTHPGDALDH1A1SMN1; SMN2NOX1
SCHEMBL42160 0.81 NOX1 (1.00) MAPTHPGDALDH1A1SMN1; SMN2NOX1
SCHEMBL29859752 0.80 MAPT (0.72) MAPTHPGDALDH1A1SMN1; SMN2MITF
SCHEMBL26935144 0.80 MAPT (0.72) MAPTHPGDALDH1A1SMN1; SMN2MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240139214-A1 AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2024-05-02 US disclosed
EP-4289422-A1 AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME Kyushu University, National University Corporation (JP) 2023-12-13 EP disclosed
CN-117042759-A IL-31 production inhibitor and pharmaceutical composition containing the same 国立大学法人九州大学 2023-11-10 CN disclosed
WO-2022168962-A1 AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME 国立大学法人九州大学 2022-08-11 WO disclosed
US-7691929-B2 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-04-06 US disclosed
US-20090186970-A1 Flame retardant compositions RONAN NICOLAS 2009-07-23 US disclosed
EP-1668073-B1 FLAME RETARDANT COMPOSITIONS CIBA HOLDING INC (CH) 2009-04-29 EP disclosed
US-20070029531-A1 Flame retardant compositions CIBA SPECIALTY CHEMICALS CORP. 2007-02-08 US disclosed
EP-1668073-A2 FLAME RETARDANT COMPOSITIONS Ciba SC Holding AG (CH) 2006-06-14 EP disclosed
WO-2005030852-A2 FLAME RETARDANT COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-04-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139214-A1 AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME IL36G, IL1RN, IL1B MAPT 3812/4885HPGD 622/4885ALDH1A1 542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.