Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263885 | 0.83 | GAA (0.58) | EPHX1GAABCHEKCNA3 | |
| SCHEMBL21786685 | 0.82 | EPHX1 (0.46) | EPHX1GAACYP2C9CYP2C19NR1H4 | |
| SCHEMBL24091968 | 0.82 | EPHX1 (0.45) | EPHX1GAABRD4BCHEKCNA3 | |
| SCHEMBL25457285 | 0.81 | ALDH1A1 (0.41) | EPHX1GAACYP2C19KMT2ABRD4 | |
| SCHEMBL19692282 | 0.81 | TPSAB1 (0.45) | EPHX1GAABRD4BCHEHDAC1 | |
| SCHEMBL22895264 | 0.81 | TPSAB1 (0.45) | EPHX1GAABRD4BCHEHDAC1 | |
| SCHEMBL17402089 | 0.81 | TPSAB1 (0.45) | EPHX1GAABRD4BCHEHDAC1 | |
| SCHEMBL19692284 | 0.81 | TPSAB1 (0.45) | EPHX1GAABRD4BCHEHDAC1 | |
| SCHEMBL16690968 | 0.80 | EPHX1 (0.54) | EPHX1GAAKMT2ABCHEKCNA3 | |
| SCHEMBL21786800 | 0.80 | EPHX1 (0.44) | EPHX1GAACYP2C19BRD4BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4065978-B1 | NOVEL LINKER COMPOUNDS | CAMBRIDGE ENTPR LTD (GB) | 2023-12-13 | — | — | EP | disclosed |