Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26935975 | 0.81 | GAA (0.62) | HPGDKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15416672 | 0.78 | LMNA (0.67) | NPC1ALDH1A1HTTSMN1; SMN2NPSR1 | |
| SCHEMBL21026152 | 0.75 | KDM4E (0.50) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL12873184 | 0.74 | NPC1 (0.49) | HPGDKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15471365 | 0.73 | LMNA (0.58) | KMT2ANPC1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL25899200 | 0.73 | NR1I2 (0.43) | HPGDKMT2AMEN1NPC1ALDH1A1 | |
| SCHEMBL15828632 | 0.72 | NPC1 (0.49) | HPGDNPC1ALDH1A1HTTRAB9A | |
| SCHEMBL21026261 | 0.71 | GABRG2 (0.44) | KMT2AMEN1HTTNPSR1LMNA | |
| SCHEMBL15473947 | 0.71 | LMNA (0.61) | KMT2ANPC1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL23479575 | 0.71 | TDP1 (0.49) | KMT2AMEN1NPC1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399332-A1 | IMIDAZO[1,2-a]PYRAZINE OR PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND USE THEREOF | TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED (CN) | 2023-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399332-A1 | IMIDAZO[1,2-a]PYRAZINE OR PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND USE THEREOF | CYP2D6, UGT1A1, TPMT | HPGD 355/4885KMT2A 2993/4885MEN1 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.