SCHEMBL2693585

SCHEMBL2693585

CCN(COC)c1nc(N(CC)COC)nc(N(CC)COC)n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
TSHR P16473 2/20 0.45
ALOX15 P16050 3/20 0.38
USP2 O75604 1/20 0.38
CRHR1 P34998 3/20 0.38
MAPT P10636 3/20 0.36
SLC29A1 Q99808 1/20 0.35
ALDH1A1 P00352 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13202805 0.98 TDP1 (0.43) TDP1TSHRALOX15USP2CRHR1
SCHEMBL16638206 0.98 TDP1 (0.43) TDP1TSHRALOX15USP2CRHR1
SCHEMBL13006380 0.98 TDP1 (0.48) TDP1TSHRALOX15USP2CRHR1
SCHEMBL16284299 0.95 TDP1 (0.47) TDP1TSHRALOX15USP2CRHR1
SCHEMBL9975766 0.93 TDP1 (0.48) TDP1TSHRALOX15USP2CRHR1
SCHEMBL16844937 0.93 TDP1 (0.48) TDP1TSHRALOX15USP2CRHR1
SCHEMBL123963 0.87 ALDH1A1 (0.38) TDP1TSHRCRHR1MAPTSLC29A1
SCHEMBL26134280 0.87 ALDH1A1 (0.38) TDP1TSHRCRHR1MAPTSLC29A1
SCHEMBL17857263 0.84 SLC29A1 (0.54) TDP1TSHRUSP2MAPTSLC29A1
SCHEMBL18805573 0.83 MAPT (0.43) TDP1TSHRALOX15USP2CRHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030213540-A1 Composite of melamine derivative and carbon black, rubber composition and article having a component thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-11-20 US claimed
EP-1362888-A1 Composite of melamine derivative and carbon black, rubber composition and article having a component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-11-19 EP claimed
US-10081221-B2 Balance pads for balancing pneumatic tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2018-09-25 US disclosed
EP-2447315-B1 Pneumatic tire with tire layer and barrier layer adhered thereto and method of making the same. GOODYEAR TIRE & RUBBER (US) 2013-09-04 EP disclosed
EP-2457750-B1 Balance pads for balancing pneumatic tires GOODYEAR TIRE & RUBBER (US) 2013-08-21 EP disclosed
EP-2457750-A1 Balance pads for balancing pneumatic tires The Goodyear Tire & Rubber Company (US) 2012-05-30 EP disclosed
US-20120125498-A1 Balance Pads For Balancing Pneumatic Tires THE GOODYEAR TIRE & RUBBER COMPANY (US) 2012-05-24 US disclosed
US-20120103487-A1 PNEUMATIC TIRE WITH TIRE LAYER AND DVA BARRIER LAYER ADHERED THERETO AND METHOD OF MAKING SAME MAJUMDAR RAMENDRA NATH (US) 2012-05-03 US disclosed
EP-2447315-A1 Pneumatic tire with tire layer and barrier layer adhered thereto and method of making the same. The Goodyear Tire & Rubber Company (US) 2012-05-02 EP disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-7132481-B2 Composite of melamine derivative and carbon black, rubber composition and article having a component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-11-07 US disclosed
US-20030213540-A1 Composite of melamine derivative and carbon black, rubber composition and article having a component thereof GOODYEAR TIRE & RUBBER COMPANY, THE 2003-11-20 US disclosed
EP-1362888-A1 Composite of melamine derivative and carbon black, rubber composition and article having a component thereof THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-11-19 EP disclosed