Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.51 |
| ▸ | THRB | P10828 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5518347 | 0.81 | HPGD (0.51) | THRATHRBHPGDPOLBALDH1A1 | |
| SCHEMBL13373993 | 0.79 | CYP2A6 (0.46) | CYP3A4CYP2D6CYP2C9HPGDPOLB | |
| SCHEMBL31497267 | 0.78 | THRA (0.53) | THRATHRBHPGDPOLBALDH1A1 | |
| SCHEMBL2098521 | 0.78 | HPGD (0.51) | THRATHRBCYP3A4HPGDPOLB | |
| SCHEMBL14127779 | 0.77 | HPGD (0.58) | HPGDPOLBALDH1A1NPSR1HTT | |
| SCHEMBL48879 | 0.77 | HPGD (0.58) | HPGDPOLBALDH1A1NPSR1HTT | |
| SCHEMBL83869 | 0.76 | CA2 (0.65) | THRATHRBCYP3A4HPGDALDH1A1 | |
| SCHEMBL2089168 | 0.76 | THRA (0.54) | THRATHRBCYP3A4ALDH1A1CA2 | |
| SCHEMBL2098522 | 0.75 | PLK1 (0.53) | CYP3A4HPGDPOLBALDH1A1NPC1 | |
| SCHEMBL28219009 | 0.74 | HPGD (0.49) | THRATHRBHPGDPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289427-A1 | DIHYDRO[1,8]NAPHTHYRIDIN-7-ONE AND PYRIDO[3,2-B][1,4]OXAZIN-3-ONE FOR USE IN TREATING CANCER, AND METASTASES IN PARTICULAR. | Anagenesis Biotechnologies (FR) | 2023-12-13 | — | — | EP | disclosed |