Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120503 | 0.77 | CHEK1 (0.40) | MRGPRX1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL10741472 | 0.77 | KMT2A (0.37) | MRGPRX1CYP1A2CYP2C19CHEK1AURKA | |
| SCHEMBL7526376 | 0.75 | HTT (0.46) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL26936506 | 0.73 | MAPK1 (0.39) | MRGPRX1CYP1A2CYP2C19CHEK1AURKA | |
| SCHEMBL1901177 | 0.73 | PKM (0.46) | CYP1A2CHEK1AURKADAPK3JAK2 | |
| SCHEMBL31674353 | 0.73 | AURKA (0.37) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL3998036 | 0.73 | AURKA (0.37) | CHEK1AURKADAPK3JAK2MAP4K4 | |
| SCHEMBL30916871 | 0.72 | ALDH1A1 (0.47) | ALDH1A1KDM4ERAB9ALMNANPC1 | |
| SCHEMBL422299 | 0.71 | CCR1 (0.48) | MRGPRX1CYP1A2CYP2C19CHEK1AURKA | |
| SCHEMBL7555908 | 0.71 | TYR (0.39) | LCKMAPK14ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4289823-A1 | SUBSTITUTED PYRIDAZINE PHENOL DERIVATIVES | Medshine Discovery Inc. (CN) | 2023-12-13 | — | — | EP | disclosed |