Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368861 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL4906865 | 0.85 | KMT2A (0.54) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL6289985 | 0.83 | PKM (0.46) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL10998213 | 0.80 | MAPT (0.46) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL24608512 | 0.80 | HTT (0.45) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL7526376 | 0.79 | HTT (0.46) | ALDH1A1KDM4ERECQLPKMGAA | |
| SCHEMBL7160198 | 0.78 | MAPT (0.58) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL7480184 | 0.78 | GABRP (0.45) | ALDH1A1KDM4EHPGDHSD17B10RECQL | |
| SCHEMBL7019066 | 0.78 | NPSR1 (0.56) | ALDH1A1KDM4EHPGDRECQLGAA | |
| SCHEMBL11578876 | 0.78 | MAPT (0.49) | ALDH1A1KDM4EHPGDHSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174304-B | Thienopyridinyl and thiazolopyridinyl compounds useful as IRAK4 inhibitors | 百时美施贵宝公司 | 2024-05-17 | — | — | CN | disclosed |